Medical Features

[Medication] Taking Ticlopidine and Clopidogrel

Post on 16/07/16

Ticlopidine and Clopidogrel lessen the chance of a harmful blood clot forming by preventing the platelets from clumping together. Ticlopidine is usually taken twice a day, and Clopidogrel once a day.

Special considerations while using Ticlopidine / Clopidogrel

  • Ticlopidine should be taken with food. This increases the amount   of Ticlopidine that is absorbed into the body. It may also lessen the chance of a stomach upset. Clopidogrel can be taken with or without food.
  • Take Ticlopidine / Clopidogrel only as directed by your doctor.
  • It is very important that blood tests be done regularly for the first few months of treatment with Ticlopidine. The tests are needed to make sure the white cell count/platelet count) in the blood does not fall. If this occurs, Ticlopidine needs to be stopped. Be sure that you do not miss any appointments for these tests.

 What should I do if I forget to take a dose?

  • If you miss a dose of Ticlopidine / Clopidogrel, take it as soon as you remember
  • However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take a double dose.

What precautions should I follow while using Ticlopidine / Clopidogrel?

  • Tell all doctors, dentists, nurses and pharmacists you go to, that you are taking Ticlopidine / Clopidogrel.
  • Do not stop taking Ticlopidine / Clopidogrel for any reason without first checking with the doctor who asked you to take it.
  • If you are going for a surgical operation, including dental procedures, please inform your doctor as Ticlopidine / Clopidogrel may need to be stopped before the procedure to prevent bleeding. The medicine may be restarted by your doctor after the procedure when appropriate.

Ticlopidine / Clopidogrel may cause serious bleeding, especially after an injury. Sometimes, bleeding inside the body can happen without you knowing. Ask your doctor whether there are certain activities you should avoid while taking this medicine. Also, check with your doctor immediately if you are injured while being treated with this medicine.

Side Effects of Ticlopidine / Clopidogrel

Check with your doctor immediately if you notice any of the following side effects:

Common side effects:

  • Mild diarrhoea
  • Mild skin rash
  • Headache, dizziness
  • Nausea
  • Bloating, gas, abdominal discomfort

Less common side effects:

  • Allergic reaction: Itching or hives, swelling in face or hands, swelling or tingling sensation in the mouth or throat, tightness in chest, trouble breathing
  • Blood in the urine
  • Bloody or black, sticky stools
  • Dark-coloured urine or light coloured stools
  • Blistering, peeling, red skin rash
  • Numbness, tingling, or burning pain in your hands, arms, legs or feet
  • Red pinpoint spots on the skin
  • Severe diarrhoea, nausea, vomiting, loss of appetite, or pain in the upper abdomen
  • Unusual bleeding, bruising, or weakness
  • Yellow skin or eyes
  • Any sign of infection, such as fever, chills or sore throat
  • Sores, ulcers or white spots in the mouth
  • Chest pain, may be related to disease and not a side effect (with Clopidogrel)
  • Joint pain or swelling (with Clopidogrel)
  • Runny or stuffy nose, cough (with Clopidogrel)

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